The Tuberculin Skin Test (TST), also known as the Mantoux test, is a diagnostic tool used to determine if an individual has been exposed to Mycobacterium tuberculosis, the bacterium responsible for tuberculosis (TB). This test is instrumental in identifying both latent TB infections and active TB disease.

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Key Features:

• Test Administration:

  • A small amount of purified protein derivative (PPD) tuberculin is injected just beneath the skin on the inner forearm.

  • The injection site is then evaluated 48 to 72 hours later by a healthcare professional to assess the body's immune response.

• Interpretation of Results:

  • The presence and size of induration (a raised, hardened area) at the injection site are measured.

  • The interpretation considers the size of the induration and the individual's risk factors for TB.

• Applications:

  • Screening: Identifying individuals who may have latent TB infection, especially those at higher risk due to factors like close contact with TB patients, weakened immune systems, or residence in areas with high TB prevalence.

  • Diagnosis: Assisting in the diagnosis of active TB disease in individuals presenting symptoms such as persistent cough, chest pain, and unexplained weight loss.

• Considerations:

  • A positive TST indicates TB exposure but does not distinguish between latent infection and active disease; further evaluation is necessary.

  • Individuals who have received the Bacillus Calmette-Guérin (BCG) vaccine may have a false-positive TST result.

  • Alternative tests, such as the Interferon-Gamma Release Assays (IGRAs), may be considered in certain situations.

For comprehensive information on the Tuberculin Skin Test, including detailed procedures, interpretation guidelines, and related considerations, please visit: https://www.testing.com/tests/tb-skin-test/

This resource provides valuable insights for healthcare providers and individuals seeking to understand the role of TST in TB detection and management.

🔗 Tuberculin Skin Test (TST) for Tuberculosis (TB)

🔗 The TB (Tuberculosis) Skin Test (Mantoux)